Crisaborole Powder Cas No.906673-24-3
Khoom Source: Synthetic
Specification: Ntau dua lossis sib npaug li 99%
CAS Nr .: 906673-24-3
Molecular Formula: C₁₄H₁₀BNO₃
Molecular Luj: 251.05 g / mol
Test Method: HPLC
Cov khoom xyaw nquag: Crisaborole
Cov yam ntxwv ntawm cov khoom: Dawb rau tawm -dawb crystalline hmoov.
Ntim Cov Khoom: 1kg / hnab; 25kg / nruas
Kev Cia Cia: Khaws rau hauv lub thawv kaw kom deb ntawm lub teeb, hauv qhov chaw qhuav, txias (2-8 degree), qhov cua zoo.
Lub neej txee: 24 lub hlis
Khoom Description
High -Quality Clobetasone Propionate API
Peb lub siab -purity clobetasone propionate API (CAS 906673-24-3), uas yog tsim los siv cov cuab yeej ua ke siab heev, yog tsim tshwj xeeb kom tau raws li cov qauv tshuaj qib. Cov khoom tau dhau los kuaj HPLC nruj, ua kom ruaj khov purity Ntau dua lossis sib npaug li 99% thiab ua raws li cov qauv tshuaj tshuaj thoob ntiaj teb xws li USP / EP.
Txhua batch yog nrog los ntawm daim ntawv pov thawj ntawm Kev Ntsuam Xyuas (COA) thiab cov ntaub ntawv taug qab, nruj me ntsis ua raws li GMP systems. Nrog rau cov saw hlau ruaj khov thiab kev txhawb nqa kev tsim kho, peb tau cog lus los muab cov neeg siv khoom siv tshuaj raws li API cov kev daws teeb meem rau atopic dermatitis.
Cov khoom muaj nuj nqi
Lub luag haujlwm tseem ceeb ntawm crisaborole yog tiv thaiv -mob. Nws zoo txo cov kev mob tshwm sim hauv daim tawv nqaij los ntawm tshwj xeeb inhibiting PDE4 enzyme, yog li txo cov tsos mob xws li liab, o, khaus, thiab daim tawv nqaij mob los ntawm atopic dermatitis. Nws lub ntsiab tseem ceeb yog tias nws tsis muaj cov tshuaj hormones, muab kev nyab xeeb thiab kev xaiv zoo rau cov neeg mob uas xav tau ntev - cov tshuaj noj lossis tshuaj rau cov chaw rhiab (xws li lub ntsej muag thiab daim tawv nqaij quav), nrog rau cov menyuam mos thiab menyuam yaus.
Cov khoom Apdaim ntawv thov
Crisaborole hmoov, raws li ib tug kws tshuaj active tshuaj muaj, yog tsuas yog siv nyob rau hauv zus tau tej cov tshuaj pleev rau sab nrauv. Cov khoom tiav lawm feem ntau yog nws 2% concentration ointment (piv txwv li, cov npe lag luam: Eucrisa, Staquis). Qhov kev npaj no tau pom zoo siv rau hauv:
• Kho mob me me mus rau nruab nrab atopic dermatitis (eczema).
• Nws tsim nyog rau ntau tus neeg, suav nrog cov neeg laus thiab menyuam yaus hnub nyoog 3 hlis lossis 2 xyoos (raws li cov ntawv pom zoo hauv ntau lub tebchaws).
Pharmacological teebmeem
1. Kev tawm tsam ntawm pro- mob cytokine ntau lawm:Nws txo qis kev tsim khoom thiab tso tawm ntau tus neeg kho mob uas cuam tshuam rau atopic dermatitis pathogenesis, suav nrog tab sis tsis txwv rau cov qog necrosis yam - (TNF- ), interleukin (IL)-2, IL{7}}4, IL-5, IL-13, thiab interferon- (IFN- ).
2. Alleviating inflammatory teb:Los ntawm kev txo qis cov tshuaj kho mob no, Clobetasol zoo tswj cov txheej txheem inflammatory hauv daim tawv nqaij, yog li txo cov tsos mob ntawm atopic dermatitis xws li erythema, edema, thiab pruritus.
Cim npe nrov: Crisaborole hmoov cas no.906673-24-3, Tuam Tshoj crisaborole hmoov cas no.906673-24-3 manufacturers, lwm tus, Hoobkas
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