Elamipretide 99% Cas No.736992-21-5

Elamipretide 99% Cas No.736992-21-5

Khoom npe: Elamipretide
Khoom npe: SS-31, MTP-131, Bendavia
Specification: Ntau dua lossis sib npaug li 98%
CAS Nr .: 736992-21-5
Molecular Formula: C₃₂H₄₉N₉O₅
Molecular Luj: 639.79 g / mol
Txoj Kev Ntsuas: HPLC
Cov khoom xyaw nquag: Elamipretide
Cov yam ntxwv ntawm cov khoom lag luam Cov yam ntxwv: Dawb rau tawm - cov hmoov dawb
Ntim: Ntau yam specifications muaj (mg, g, kg), customizable
Cia txias: -20℃± 5 degree, khaws cia rau hauv qhov chaw qhuav, tiv thaiv lub teeb
Lub neej txee: 36 lub hlis

Kev Tshaj Tawm Txog Kev Siv: Cov khoom no yog tsim los siv rau kev lag luam lossis kev tshawb fawb tshawb fawb nkaus xwb.
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Khoom Description

Peb tshwj xeeb hauv kev muab siab -purity Elamipretide cov khoom xyaw tshuaj nquag (APIs), uas nruj me ntsis ua raws li cov qauv tshuaj zoo thiab ua tau zoo tshaj qhov yuav tsum tau tshawb fawb. Peb cov APIs ua tau raws li qhov xav tau nruj ntawm cov qauv tsim tshiab thoob plaws txhua theem, txij li thaum ntxov -theem kev txhim kho mus rau kev tsim khoom lag luam.

Peb nkag siab tag nrho cov kev xav tau ntawm kev tsim kho tshuaj, yog li muab cov khoom lag luam hloov pauv hloov pauv hloov pauv txij li gram - nplai rau kilogram - nplai ntau. Qhov no ua kom peb cov neeg tau txais cov khoom siv raws sijhawm thiab txhim khu kev qha thoob plaws txhua theem ntawm lawv cov kev tshawb fawb. Peb tau cog lus los ua koj tus khub muaj kev vam meej.

Pharmacological Action

Elamipretide yog ib lub xovtooj ntawm - nkag mus rau hluavtaws tetrapeptide uas nws lub luag haujlwm tseem ceeb ntawm kev siv tshuaj yog txhawm rau tsom thiab txhim kho kev ua haujlwm mitochondrial. Nws hla cov cell membranes sai sai thiab accumulates nyob rau hauv mitochondria, exerting cov teebmeem xws li muaj zog tiv thaiv -inflammatory, antioxidant, thiab anti-apoptotic kev ua ub no los ntawm stabilizing mitochondrial qauv thiab lub zog metabolism.

Mechanism ntawm Action

Nws cov txheej txheem ntawm kev ua haujlwm yog los ntawm kev khi tshwj xeeb rau cardiolipin, phospholipid tshwj xeeb pom nyob rau hauv mitochondrial membrane mitochondrial membrane.

1. Stabilizes Electron Transport Chain (ETC): Los ntawm kev khi rau cardiolipin, nws pab txhim kho cov qauv ntawm mitochondrial respiratory chain (ETC) supercomplexes, yog li optimizing cov efficiency ntawm adenosine triphosphate (ATP) ntau lawm.

2. Txo Reactive Oxygen Species (ROS) Ntau Lawm: Los ntawm kev txhim kho kev ua haujlwm ntawm kev hloov hluav taws xob, nws txo cov hluav taws xob xau ntawm qhov chaw, txo qis qhov overproduction ntawm ROS, yog thawj tsav tsheb ntawm oxidative kev nyuaj siab.

3. Khaws Mitochondrial Membrane Integrity: Los ntawm stabilizing cardiolipin, nws pab tiv thaiv lub pathological qhib ntawm mitochondrial permeability hloov pore (mPTP), yog li inhibiting qhov pib ntawm apoptosis.

Khoom Description

Hauv kev tshawb fawb preclinical thiab kho mob, cov khoom xyaw nquag no tau pom tias muaj peev xwm ua tau raws li hauv qab no:

• Txhim kho Cellular Energy Metabolism: Restores ATP ntau lawm muaj peev xwm nyob rau hauv lub hlwb tsis zoo.

• Alleviates Oxidative Stress Damage: Ua kom muaj txiaj ntsig zoo thiab txo cov kab mob oxygen reactive.

• Tiv thaiv Cells los ntawm Kev Tuag: Tiv thaiv cov kab mob apoptosis los ntawm ntau yam los ntawm kev tswj hwm mitochondrial kev ncaj ncees.

• Txhim kho Tissue Function: Qhia tau tias muaj peev xwm txhim kho kev ua haujlwm ntawm ntau cov ntaub so ntswg xws li lub plawv, paj hlwb, thiab cov leeg.

Khoom siv

Raws li qib siab -cov khoom siv tshuaj muaj txiaj ntsig zoo (API), nws feem ntau yog siv rau hauv kev tshawb fawb thiab kev tsim kho, thiab kev tsim tshuaj rau thaj chaw hauv qab no:

• Kab Mob plawv: Kev tsim cov tshuaj rau tej yam mob xws li myocardial ischemia-reperfusion raug mob thiab mob plawv tsis ua hauj lwm.

• Cov Kab Mob Neurodegenerative: Kev tshawb fawb txog kev kho tshiab rau cov kab mob neurological xws li Alzheimer's disease thiab Parkinson's disease.

• Cov Kab Mob Tsis tshua muaj: Raws li qhov muaj peev xwm kho tau rau Barth Syndrome, uas nws tau txais cov npe tshuaj me nyuam ntsuag los ntawm cov koom haum tswj hwm.

• Lwm yam Mitochondrial Dysfunction-Txoj Kev Tsis Txaus Siab: Xws li hnub nyoog- ntsig txog macular degeneration thiab qee hom mob raum.

Tsis lees paub

Cov ntaub ntawv saum toj no yog ua raws li kev tshawb fawb tshawb fawb thiab cov ntaub ntawv kho mob pej xeem thiab tsuas yog siv rau kev siv xwb. Cov khoom no yog Active Pharmaceutical Ingredient (API) tsuas yog siv los ntawm cov kws tshaj lij hauv kev tshawb fawb tshuaj, kev tsim kho, thiab kev tsim khoom. Nws yog txwv tsis pub siv ncaj qha rau tib neeg lossis kev tswj hwm raws li cov tshuaj tiav.

Cim npe nrov: elamipretide 99% cas no.736992-21-5, Tuam Tshoj elamipretide 99% cas no.736992-21-5 manufacturers, lwm tus neeg, Hoobkas

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