Abaloparatide hmoov CAS No.247062-33-5
Tau qhov twg los: Synthetic
Specification: Ntau dua lossis sib npaug li 98%
CAS Nr .: 247062-33-5
Molecular Formula: C₁₇₄H₃₀₀N₅₆O₄₉
Molecular Luj: ≈ 3960 Da
Txoj Kev Xeem: HPLC
Cov khoom xyaw nquag: Abaloparatide
Cov yam ntxwv ntawm cov khoom lag luam Cov yam ntxwv: Dawb los yog tawm -dawb lyophilized hmoov
Ntim: 1-100 g / vial; 1 kg / aluminium ntawv ci hnab; 25 kg / nruas
Cia txias: Khaws ntawm -20℃± 5 degree, tiv thaiv lub teeb thiab noo noo
Lub neej txee: 24 lub hlis
Kev Tshaj Tawm Txog Kev Siv: Cov khoom no yog tsim los siv rau kev lag luam lossis kev tshawb fawb tshawb fawb nkaus xwb.
Khoom Description
Peb tshwj xeeb hauv kev tsim khoom thiab muab cov khoom siv siab -purity abapentanapeptide active pharmaceutical ingredient (API). Leveraging advanced tag nrho cov cuab yeej siv tshuab thiab cov kev tswj xyuas nruj, peb cov khoom pov thawj zoo tib yam tshuaj thiab lub cev rau cov qauv siv. Peb lub peev xwm tsim muaj peev xwm tuaj yeem ua tau raws li koj cov kev xav tau thoob plaws txhua theem, los ntawm kev tshawb fawb soj ntsuam mus rau kev tsim khoom lag luam.
Peb tau cog lus los muab cov neeg siv khoom txhim khu kev qha ua tau raws li cov qauv kev lag luam nruj thiab kev txhawb nqa cov saw hlau, ua haujlwm raws li koj tus khub kev ntseeg siab.
Pharmacological Action
Abaloparatide yog cov tshuaj hluavtaws polypeptide uas tau muab cais ua tus neeg sawv cev ntawm lub cev. Nws cov tshuaj pharmacological tseem ceeb yog txhawm rau txhim kho cov pob txha tshiab. Thaum nws nruab nrab nce pob txha resorption, tag nrho cov txiaj ntsig yog qhov nce ntawm cov pob txha loj thiab txhim kho pob txha microarchitecture.
Mechanism ntawm Action
Raws li ib qho piv txwv ntawm tib neeg cov tshuaj hormones parathyroid-txog cov protein (PTHrP), Abaloparatide yog ib qho kev xaiv, siab -affinity agonist ntawm parathyroid hormone type 1 receptor (PTH1R). Raws li kev khi rau PTH1R, nws nyiam thiab txhawb nqa Gs / cAMP / PKA txoj kev taw qhia (txoj kev canonical). Qhov kev ua kom muaj zog tshwj xeeb no ua rau nws muaj peev xwm txhawb nqa osteoblast kev loj hlob thiab kev sib txawv, ua kom pom kev ua tau zoo tshaj plaws hauv kev txhawb nqa cov pob txha tshiab piv rau cov kev kho mob ib txwm muaj, thaum muaj kev cuam tshuam tsis muaj zog ntawm osteoclast- kho pob txha resorption. Qhov no ua rau lub qhov rais anabolic dav dua.
Product Efficiency
| Qhov tseem ceeb nce hauv pob txha Mineral Density (BMD) | Cov txiaj ntsig zoo hauv BMD tau pom nyob rau ntawm qhov chaw tseem ceeb, suav nrog lumbar qaum thiab lub duav. |
| Kev txo qis ntawm kev pheej hmoo tawg |
Los ntawm kev txhim kho cov pob txha muaj zog thiab txhim kho pob txha zoo, nws txo qis kev pheej hmoo ntawm pob txha pob txha thiab cov pob txha tsis muaj pob txha hauv cov poj niam tom qab yug me nyuam nrog osteoporosis. |
Khoom siv
Raws li qib siab -purity Active Pharmaceutical Ingredient (API), nws cov ntawv thov tseem ceeb yog:
| Pharmaceutical Manufacturing | Siv hauv kev tsim cov khoom siv tshuaj zaum kawg (xws li cov tshuaj txhaj tshuaj) qhia rau kev kho cov poj niam postmenopausal nrog osteoporosis ntawm kev pheej hmoo rau pob txha. |
| Kev Tshawb Fawb & Kev Txhim Kho | Siv nyob rau hauv txoj kev loj hlob ntawm tshiab tshuaj xa systems (xws li, transdermal thaj ua rau thaj, qhov ncauj formulations), generic tshuaj tshawb fawb, thiab ntxiv kev tshawb fawb rau cov mechanisms ntawm skeletal metabolic kab mob. |
Cim npe nrov: abaloparatide hmoov cas no.247062-33-5, Tuam Tshoj abaloparatide hmoov cas no.247062-33-5 manufacturers, lwm tus neeg, Hoobkas
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