Lanreotide Powder Cas No.108736-35-2

Peb tshwj xeeb hauv kev muab siab -purity Lanreotide active pharmaceutical ingredient (API). Peb nkag siab tag nrho cov kev cai nruj nruj rau cov khoom siv raw hauv kev tshawb fawb thiab kev tsim tshuaj. Yog li ntawd, peb cov khoom ua raws li cov qauv kev tsim khoom nruj heev los ntawm qhov pib, ua kom lawv lub cev muaj zog, purity, thiab ruaj khov ua tau raws li cov txheej txheem kev xav tau.

Txhawm rau kom txhawb nqa koj R&D thiab kev lag luam mus rau kev lag luam, peb muab ntau yam kev hloov pauv hloov pauv hloov pauv - los ntawm chav kuaj - qib milligram thiab gram ntau rau kilogram - nplai batch rau loj - nplai ntau lawm. Peb ua tsaug caw koj los txiav txim siab rau peb koj tus neeg koom tes hauv cov khoom lag luam uas ntseeg siab, ua haujlwm ua ke los tuav lub sijhawm ua lag luam.

Lanreotide yog qhov ntev - ua yeeb yam somatostatin analog. Nws cov tshuaj pharmacological tseem ceeb suav nrog kev ua raws li cov tshuaj endogenous somatostatin kom dav inhibit lub secretory functions ntawm ntau yam endocrine thiab exocrine qog. Nws muaj peev xwm thiab xaiv tau inhibits pathological overproduction ntawm kev loj hlob hormone (GH), insulin-zoo li kev loj hlob factor-1 (IGF-1), gluc), glucagon, insulin, thiab ntau yam kab mob hauv plab (xws li gastrin, vasoactive plab hnyuv peptide, thiab secretin).

Cov txheej txheem ntawm kev ua ntawm lanreotide yog ua raws li nws qhov siab - kev sib koom ua ke rau qee yam somatostatin receptors (SSTRs), tshwj xeeb tshaj yog subtypes SSTR2 thiab SSTR5, ntawm cov cell membranes. Qhov kev khi no ua rau muaj kev cuam tshuam ntawm intracellular teeb liab transduction txheej xwm, thaum kawg ua rau:

1. Inhibition of Hormone Secretion: Los ntawm kev kaw cov calcium channels thiab modulating poov tshuaj raws ntawm cell membranes, nws ncaj qha suppresses tso tawm cov hom tshuaj hormones.

2. Kev Tiv Thaiv Kev Loj Hlob ntawm Cell: Los ntawm kev ua kom muaj protein ntau tyrosine phosphatase, nws cuam tshuam nrog cov cim mitogenic, yog li inhibiting kev loj hlob txawv txav hauv qee cov qog hlwb.

3. Kev txo cov ntshav: Los ntawm inhibiting zus tau tej cov yam xws li vascular endothelial kev loj hlob factor (VEGF), nws indirectly txo cov ntshav txaus mus rau lub hom phiaj cov ntaub so ntswg (xws li, qog).

Raws li cov khoom siv tshuaj nquag (API), qhov ua tau zoo ntawm lanreotide tau tshwm sim hauv cov txiaj ntsig kho mob tau ua tiav los ntawm nws cov khoom siv tshuaj. Raws li cov ntaub ntawv pov thawj zoo, nws cov teebmeem kev kho mob tseem ceeb suav nrog:

• txo qis qib ntawm kev loj hlob hormone (GH) thiab insulin ntau heev-zoo li kev loj hlob-1 (IGF-1), yog li tswj cov kab mob kev loj hlob thiab cov tsos mob cuam tshuam hauv acromegaly.

• Tswj tau zoo cov tsos mob cuam tshuam nrog cov qog ua haujlwm neuroendocrine, xws li dej ntws tawm thiab raws plab los ntawm carcinoid syndrome.

• inhibiting kev loj hlob ntawm ntau yam qog nqaij hlav secretory los ntawm nws cov teebmeem antiproliferative.

Cov khoom no yog cov khoom siv tshuaj nquag (API) thiab feem ntau siv hauv cov hauv qab no:

• Kev Tsim Kho Tshuaj thiab Kev Tsim Tshuaj: Siv rau hauv kev npaj ntev - ua haujlwm ruaj khov - tso tawm cov tshuaj txhaj tshuaj ntawm lanreotide (piv txwv li, ua ntej- cov koob txhaj tshuaj, cog qoob loo).

• Innovative Formulation Research: Ua lub luag haujlwm tseem ceeb hauv kev tsim cov tshuab xa tawm tshiab (xws li microspheres, nanoparticles) txhawm rau txhim kho cov tshuaj tso tawm cov yeeb yaj kiab thiab txhim kho kev ua raws li tus neeg mob.

• Kev Siv Tshuaj Siv Tshuaj: Muab cov khoom muaj txiaj ntsig zoo - zoo rau kev tsim cov tshuaj uas muaj tshuaj sib npaug thiab kho tau zoo sib npaug rau cov khoom tsim tawm.

• Txiav-Txoj Kev Tshawb Fawb Txog Kev Tshawb Fawb: Kev ua haujlwm raws li cov qauv kev tshawb fawb lossis cov ntaub ntawv siv los txhawb kev tshawb nrhiav kev tshawb fawb hauv lwm cov kev qhia muaj peev xwm (xws li lwm hom qog nqaij hlav, kab mob ophthalmic).

Cov ntaub ntawv saum toj no yog ua raws li kev tshawb fawb txog kev tshawb fawb thiab cov ntaub ntawv kho mob pej xeem thiab yog siv rau kev siv nkaus xwb. Cov khoom no yog cov khoom siv tshuaj nquag siv tshuaj (API) tsuas yog siv los ntawm cov kws tshaj lij hauv kev tshawb fawb tshuaj, kev tsim kho, thiab kev tsim khoom. Nws yog txwv tsis pub siv ncaj qha rau tib neeg lossis kev tswj hwm raws li cov khoom siv tshuaj tiav.

Cim npe nrov: lanreotide hmoov cas no.108736-35-2, Tuam Tshoj lanreotide hmoov cas no.108736-35-2 manufacturers, lwm tus neeg, Hoobkas