Eptifibatide hmoov CAS No.188627-80-7

Peb tshwj xeeb hauv kev tsim cov qib siab -purity Eptifibatide cov khoom siv tshuaj nquag (API). Cov khoom no yog crystalline hmoov ntawm nruj dawb los yog tawm - xim dawb, nrog rau qhov ruaj khov purity ntau tshaj 99%.

Peb Eptifibatide ua tau raws li kev siv tshuaj nruj heev- cov qauv qib thoob plaws txhua qhov kev ntsuas tseem ceeb, ua kom txaus siab raws li cov kev xav tau los ntawm kev tshawb fawb thiab kev tsim kho mus txog rau kev tsim khoom lag luam. Pom tau tias API zoo ua rau muaj kev nyab xeeb ntawm cov tshuaj thiab kev ua tau zoo, peb cog lus rau kev tswj xyuas kom zoo rau txhua pawg. Qhov no ua kom muaj zog glycoprotein IIb / IIIa receptor inhibitory kev ua haujlwm, muab lub hauv paus ruaj khov thiab txhim khu kev qha rau koj qhov kev tsim kho tom ntej.

Eptifibatide yog ib qho zoo heev antiplatelet tus neeg sawv cev rau cov chav kawm ntawm glycoprotein IIb / IIIa receptor antagonists. Nws cov tshuaj pharmacological cuam tshuam tshwj xeeb los thaiv txoj hauv kev kawg ntawm platelet aggregation, yog li muaj zog inhibiting qhov tsim ntawm platelet thrombi. Nws ua sai sai, ua rau cov nyhuv antiplatelet tam sim ntawd tom qab txhaj tshuaj. Tsis tas li ntawd, raws li nws qhov kev txiav txim yog thim rov qab, platelet muaj nuj nqi rov qab sai sai tom qab qhov kev txhaj tshuaj raug tso tseg.

Raws li ib txwm muaj lub cev muaj zog, platelets tau qhib thaum cov hlab ntsha raug mob. Cov activated glycoprotein IIb / IIIa receptors ntawm platelet nto tau hloov pauv, ua rau lawv khi nrog siab affinity rau ligands xws li fibrinogen. Fibrinogen ua tus choj, hla- txuas GP IIb / IIIa receptors uas nyob ib sab ntawm cov platelets nyob ze, ua rau tsim cov platelet aggregates.

Raws li cyclic heptapeptide, Eptifibatide tus qauv ua raws li ib feem ntawm fibrinogen molecule, tso cai rau nws khi rau cov receptor no tshwj xeeb thiab sib tw. Los ntawm kev tuav cov chaw receptors, Eptifibatide zoo tiv thaiv fibrinogen losis tswvyim dabtsi, txiav cov "choj" ntawm platelets thiab yog li inhibiting aggregation ntawm nws cov kauj ruam tseem ceeb tshaj plaws.

Raws li Cov Khoom Siv Tshuaj Siv Tshuaj (API), qhov ua tau zoo ntawm Eptifibatide nyob rau hauv muab cov txiaj ntsig kho mob hauv qab no rau cov qauv hauv qab (xws li cov tshuaj txhaj tshuaj):

Cov nyhuv Antithrombotic muaj zog: Ua kom muaj zog inhibition ntawm platelet aggregation los ntawm kev thaiv ntau tshaj 80% ntawm GP IIb / IIIa receptors.

Kev txo qis hauv Ischemic Cov Txheej Txheem: Cov ntawv thov kho mob tau ua pov thawj nws cov txiaj ntsig hauv kev txo qis kev pheej hmoo ntawm cov xwm txheej mob ischemic, xws li kev tuag thiab myocardial infarction myocardial infarction, hauv cov neeg mob uas mob plawv mob plawv uas tau txais Percutaneous Coronary Intervention.

Kev pib nrawm nrawm thiab tswj tau: Nws cov ntaub ntawv tshuaj pharmacokinetic pab txhawb kev cuam tshuam sai thiab tswj koob tshuaj hauv cov chaw kho mob hnyav.

Eptifibatide API feem ntau yog siv rau hauv kev tsim cov ntawv siv tshuaj zaum kawg rau cov chaw hauv qab no:

Acute Coronary Syndrome (ACS): Siv los kho cov neeg mob uas tsis ruaj khov angina lossis tsis yog -ST- ntu nce myocardial infarction los tiv thaiv cov xwm txheej mob plawv.

Percutaneous Coronary Intervention (PCI): Muab rau cov neeg mob uas tau txais PCI (txawm tias stented lossis tsis) txhawm rau tiv thaiv kev tsim cov thrombus hauv cov hlab ntsha hauv lub sijhawm thiab sai tom qab cov txheej txheem. Nws yog ib feem tseem ceeb ntawm peri- txheej txheem tshuaj tiv thaiv kab mob.

Daim ntawv ceeb toom tseem ceeb:Cov ntaub ntawv saum toj no yog ua raws li cov ntaub ntawv tshawb fawb txog pej xeem thiab cov yam ntxwv ntawm cov khoom. Kev siv cov khoom tsim tawm kawg yuav tsum ua raws li cov ntaub ntawv sau npe pom zoo thiab cov lus qhia ntawm cov kws kho mob.

Cim npe nrov: Tuam Tshoj eptifibatide hmoov cas no.188627-80-7 manufacturers, lwm tus neeg, Hoobkas