Memantine Hydrochloride Cas No.51052-62-1

Memantine hydrochloride yog cov tshuaj nquag hauv cov tshuaj npaj siv los kho cov kab mob hauv lub paj hlwb, tshwj xeeb yog Alzheimer's disease.

Melting Point: 118-119 degree

Boiling Point: 395.9℃ntawm 760 mmHg

Qhov ceev: 1.168 g / cm³

Vapor Siab: 1.78 × 10⁻⁶ mm Hg ntawm 25 degree

Refractive Index: 1.518

Flash point: 193.2 degree

Solubility: Soluble hauv dej (34 mg / mL ntawm 25 degree), DMSO (34 mg / mL ntawm 25 degree), thiab ethanol (34 mg / mL ntawm 25 degree)

Daim ntawv: Crystalline hmoov

Raws li ib qho tshuaj active ingredient, memantine hydrochloride feem ntau yog ua tiav rau hauv ntau hom tshuaj (xws li ntsiav tshuaj, tshuaj ntsiav, thiab tshuaj qhov ncauj) rau kev kho mob. Nws txoj haujlwm kho mob yog los ua tus neeg saib xyuas neuroprotective los ntawm kev tswj cov glutamate hauv lub hlwb.

Siv rau hauv kev lag luam tawm txawv teb chaws, kev tshawb fawb tshawb fawb, thiab tshuaj reagents.

Memantine hydrochloride noncompetitively thaiv NMDA receptors, txo glutamate-induced NMDA receptor hyperactivation thiab tiv thaiv apoptosis, yog li txhim kho kev nco thiab txhim kho kev txawj ntse hauv cov neeg mob. Chemicalbook Vim yog memantine hydrochloride qhov qis mus rau nruab nrab affinity rau NMDA receptors, nws thaiv glutamate excitotoxicity yam tsis cuam tshuam nrog glutamate lub physiological luag hauj lwm nyob rau hauv ib txwm kev kawm thiab nco dab.