Epalrestat Powder Cas No.82159-09-9

Xi'an Tihealth High Purity Epalrestat

Xi'an Tihealth muab tshuaj qib siab -purity Epastatin raw cov ntaub ntawv. Cov ntsiab lus tseem ceeb ntawm cov khoom yog ruaj khov ntawm Ntau dua lossis sib npaug li 98% (kuaj los ntawm HPLC) thiab ua tau raws li tus qauv qauv. Raws li ib qho tseem ceeb aldose reductase inhibitor, cov khoom no tau mob siab rau kev tshawb fawb, kev tsim kho thiab tsim cov tshuaj rau kev kho mob ntshav qab zib neuropathy. Peb muab cov ntim khoom hloov tau yooj yim (los ntawm kev tshawb fawb thiab kev tsim qauv mus rau cov khoom siv ntau lawm), thiab khaws cia thiab thauj khoom raws li kev tswj hwm qhov kub thiab txias (pom zoo -20 degree) thiab tsaus thiab qhuav kom ntseeg tau cov khoom ruaj khov thiab muab kev ruaj ntseg lav rau koj cov dej num.

Ipastatin inhibits qhov kev ua ntawm aldose reductase (AR), thaiv qhov txawv txav ntawm sorbitol txoj hauv kev raug ntxias los ntawm hyperglycemia, txo cov sorbitol thiab fructose nyob rau hauv cov paj hlwb, thiab yog li alleviates paj fiber ntau degeneration thiab demyelination. Tshwj xeeb manifested nyob rau hauv:

Cov tsos mob nyem, kho cov hlab ntsha, ntshav ntws rov qab los

1. Multidimensional kev txhim kho ntawm ntshav qab zib neuropathy

2. Kev tiv thaiv lub raum thiab kev tswj cov metabolism

3. Kev tiv thaiv kab mob thiab kev tiv thaiv kab mob

Txo glycation kawg khoom (AGEs) thiab antioxidant kev nyuaj siab

Ipastatin tuaj yeem cuam tshuam qhov kev qhia ntawm pro- cov kab mob inflammatory xws li interleukin-1 (IL-1) thiab qog necrosis factor - (TNF - ), alleviate neurointimal o, tswj lub cev tiv thaiv kab mob kev ua haujlwm, thiab txo qhov kev pheej hmoo ntawm necrosis rov tshwm sim.

1. Kev kho mob ntawm cov mob ntshav qab zib:

• Mob ntshav qab zib peripheral neuropathy (DPN): txhim kho limb loog, mob thiab paresthesia.

• Mob ntshav qab zib retinopathy: ncua qhov tsis pom kev los ntawm microvascular puas.

2. Kev tsim tshuaj: cov khoom siv raw siv rau cov tshuaj kho DPN (xws li ntsiav tshuaj, tshuaj ntsiav).

1,Lub hom phiaj inhibition:

Selectively khi rau qhov chaw nquag ntawm aldose reductase, inhibiting nws lub peev xwm los ua kom cov piam thaj hloov mus rau sorbitol.

2,Pathological kho:

Txo cov intracellular sorbitol concentration, restores osmotic siab tshuav, alleviates edema thiab oxidative kev nyuaj siab puas nyob rau hauv paj hlwb, thiab kho cov hlab ntsha conduction muaj nuj nqi.