Plecanatide hmoov CAS No.467426-54-6
Lus Askiv lub npe: Trulance; Plectide
Cov ntsiab lus tshwj xeeb: Ntau dua lossis sib npaug li 98%
CAS Nr .: 467426-54-6
Txoj kev kuaj pom: HPLC
Cov khoom xyaw nquag: Pucanapeptide (ib qho cyclic peptide muaj li ntawm 16 amino acids)
Cov tshuaj formula: C ₆₅ H ₁₀₄ N ₁₈ O ₂₆ S ₄
Molecular Luj: 1681.89 g / mol
Cov lus piav qhia: Dawb rau cov khoom dawb
Khoom siv: CIC; IBS-C
Cov khoom ntim: 1G / Lub raj mis, 10G / Lub raj mis, 50G / Lub raj mis lossis ntawm cov neeg siv khoom xav tau.
Cov khoom cia: 20 ° C - 25 ° C (chaw kub), tso cai rau lub sijhawm luv luv mus txog 15 ° C-30 ° C
Lub neej txee: hmoov: ntim cia ntawm -20℃C (1 xyoos); -80 ° C (2 xyoos)
Khoom Description
Plecanatide hmoov nrog siab purity los ntawm Tihealth
Xi'an TihealthBiotechnology tshwj xeeb hauv kev muab siab -purity Plecanatide raw cov ntaub ntawv, nrog ib tug ruaj khov purity ntawm Greater los yog sib npaug li 98% (tsim los ntawm HPLC), raws li USP/EP pharmacopoeia cov qauv. Cov khoom siv cov khoom siv-theem fragment synthesis thev naus laus zis thiab ua raws li kev tswj hwm nruj (HPLC, huab hwm coj spectrometry, thiab disulfide daim ntawv cog lus kev taw qhia) kom ntseeg tau cov qauv sib xws (CAS 467426-54-6) thiab qis endotoxin (<0.1 IU/mg). Flexible customization of specifications (10mg-1g) can meet the needs of drug development, formulation production, and clinical research. Raw materials are packaged in sealed and light resistant packaging (frozen at -20 ℃).
Raws li cov khoom tseem ceeb ntawm cov tshuaj kho cem quav (CIC/IBS-C), cov khoom no txhim kho cov kua hauv plab los ntawm kev tsom mus rau kev ua kom GC-C receptors. Nws tsis tshua muaj bioavailability tuaj yeem txo qhov kev pheej hmoo ntawm kev mob tshwm sim. Peb txhawb kev tsim cov tshuaj tshiab rau kev noj qab haus huv hauv plab nrog cov tshuaj qib zoo. Peb txais tos nug rau kev koom tes.
Cov khoomCov txiaj ntsig
1, Ua kom lub plab zom mov, ua kom cov quav mos, thiab ua kom lub plab hnyuv
2, Ib feem tsis ua haujlwm nyob rau hauv cov cheeb tsam acidic, txo cov plab hnyuv loj, thiab txo qis kev pheej hmoo ntawm raws plab.
Cov khoomKev thov
1/Formulation ntau lawm,
2/ Kev tsim tshuaj tshiab,
3/ Kev tshawb fawb soj ntsuam,
4/Diagnostic reagents
Khoom zoo
Ib qho kev tswj xyuas nruj nruj tuaj yeem ua kom muaj purity siab zoo thiab tsis tshua muaj impurity tswj.
Mechanism ntawm kev ua
Plecanatide thiab nws cov metabolites nquag khi rau GC-C enzyme thiab ua haujlwm hauv zos rau ntawm qhov chaw luminal ntawm txoj hnyuv epithelial hlwb. Kev ua haujlwm ntawm GC-C enzyme nce qhov concentration ntawm cyclic guanosine monophosphate (cGMP) ob sab hauv thiab sab nraud ntawm tes, thaum qhov nce hauv intracellular cGMP concentration yog ua tiav los ntawm kev ua kom cov ion channels ntawm cystic fibrosis transmembrane regulator (CFTR), uas txhawb nqa cov kua qaub thiab chloride. bicarbonate mus rau hauv txoj hnyuv lumen, nce thiab ceev cov kab mob ntawm cov hnyuv me.
Cim npe nrov: Tuam Tshoj plecanatide hmoov cas no.467426-54-6 manufacturers, lwm tus neeg, Hoobkas
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