Cetrorelix acetate hmoov yog tsis muaj . 120287-85-6
Khoom siv: hluavtaws
Cov ntsiab lus cov khoom: Ntau dua los yog sib npaug rau 98%
Tus lej lej: 120287-85-6
Kev Nrhiav Kom Paub: HPLC
Nquag xyaw: Cetrorelix Acetate
Cov Khoom Lag Luam: Dawb rau Dawb
Khoom Mesh: 80-120 mesh
Cov Khoom Siv Siv: Pab cov tshuab kev ua me nyuam (kos duab), kev kho mob gynrecological, kev tshawb fawb
Cov khoom ntim khoom: Lyophilized hmoov: feem ntau ntim rau hauv iav ampoules los yog cov khoom siv txhuas los yog xws li 1mg, 5mg, 10mg, thiab lwm yam).
Daim ntawv ua kua: Yuav tsum muaj cov vials squines tsis huv lossis vials, nrog cov kuab pa ntim cais cais.
Cov khoom lag luam cia: feem ntau khaws cia rau hauv ib lub teeb - pov thawj, ib puag ncig ib puag ncig ntawm 2-8 degree.
Txee Lub Neej: Thaum tsis muaj qhov thaiv thiab khaws cia ntawm 2 - 8℃hauv lub teeb pom kev zoo, lub txee lub neej ib txwm muaj 2-3 xyoos.
Cov khoom lag luam
Cetrorelix acetate Hmoov yog ib qho hluavtaws gonadotropin {}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}} Cov qauv tshuaj lom neeg ntawm ib lub cyclic decapeptide derivative. Nws kev sib tw khi rau GNRH receptor nyob rau hauv lub anterior piluitary caj dab, inhibiting qhov kev tawm ntawm cov tshuaj hormones endogen Qhov no sib xyaw no feem ntau yog muab nyob rau hauv daim ntawv ntawm khov - txaus} qhuav hmoov thiab yuav tsum tau yaj ua ntej siv.
Pharmacological cuam tshuam
Cetrorelix acetate hmoov yog gonadotropin - tso tawm cov tshuaj tiv thaiv (Gnrh) kev thaiv. Nws ua haujlwm los ntawm kev sib tw los ntawm kev sib tw rau thiab thaiv cov gnrh recitors hauv cov tshuaj pituitary ntawm Luteinizing Hormone (LH)- attadulating hormone (fsh) zais cia. Qhov no yog qhov tseem ceeb hauv kev kos duab rau inhibiting endogenous lh surge thiab tiv thaiv kev ua kom ntxov ntxov. Nws cov nyhuv supressive yog sai thiab thim rov qab, nrog pituitary muaj nuj nqi rov qab sai tom qab cov tshuaj nres.
Mechanism ntawm Kev Ua
Cetrorelix acetate hmoov, kuj nquag hu ua cetrorelix, kuj yog ib qho txiaj ntsig progesterone {{0} - rh) releptor kev thaiv. Nws tuaj yeem tswj lub zes qe menyuam, tiv thaiv kev tso tawm ntxov ntxov, thiab ua kom yooj yim rau kev tawm tswv yim. Yog li ntawd, nws feem ntau siv los ua kev npaj cetorelix thib.
Npaj rau
Cov poj niam cov neeg mob tau txais cov kev tswj hwm lub zes qe me ntsis (xws li kev kho mob ntxiv). Cov neeg mob nrog cov kab mob gynecological uas yuav tsum muaj kev tswj hwm kev ua, xws li endometriosis.
Kev ua tau zoo thiab thov kev xaiv cov xwm txheej ntawm cov khoom
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LEEG HOM |
Kev Qhia Tshwj Xeeb |
Thawj cov ntsiab lus thov |
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Tub Ntxhais Txawj Ntse |
Tiv thaiv kev ua kom ntxov ovulation thaum tswj lub qe qe menyuam qe menyuam (cos) |
Ovarian Stimulation Muscles hauv pab kev pab tsim me nyuam thev naus laus zis (piv txwv li, IVF) |
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Tseem ceeb nkaus |
Inhibits Lutinizing Hormone (LH) |
Ua kom muaj sijhawm txaus rau lub follicle maturation, txhim kho tus lej thiab cov qe zoo ntawm cov qe |
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Cov txiaj ntsig ntxiv |
Txo qhov kev pheej hmoo ntawm zes qe menyuam hypuam kev ntxhov siab (Ohss) |
Thaum siv gonadotropins rau lub zes qe |
|
Pharmacological |
Cov blocks sib tw pituitary gnrh recept, sai sai inhibits lub zais ntawm lh thiab fsh; Qhov cuam tshuam yog thim rov qab tom qab tsis sib haum |
Kev kho cov xwm txheej yuav tsum tau kho nrawm thiab rov qab los ntawm kev ua haujlwm Axis muaj nuj nqi |
|
Lwm cov ntawv thov yuav |
Tej zaum yuav txhim kho cov endometriosis -}} pitticamic-} pitfaticity}}}}: cov lus no tsis yog lub ntsiab lus) |
Kev tshawb fawb txog kev cuam tshuam rau cov kev cuam tshuam lossis cov txiv neej fertility txhim kho (yuav tsum tau tshuaj xyuas kev kho mob nruj) |
Cim npe nrov: Cetrorelix acetate hmoov tsis muaj}}}}}}
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