Folic Acid Hmoov
Lwm lub npe: Vitamin B9
Lub npe tshuaj: Npauj Npaim acid glutamic acid
Lub npe Askiv: Vitamin B9
Xim: Lub teeb daj siv lead ua
Khoom specification: 99%
Ntim txoj kev: 1KG / aluminium ntawv ci hnab, 25KG / ntawv raj ntim
Cia txoj kev: qhuav, txias, kaw, deb ntawm lub teeb, ventilated
Lub sijhawm siv tau: 24 lub hlis
Bulk Folic Acid Powder (Vitamin B9)|USP/EP Qib API & Khoom noj khoom haus Fortificant
Hwm Pharmaceutical & Nutritional Base los ntawmXi'an Tihealth
Hauv ntiaj teb kev noj zaub mov ntxiv thiab cov kev pab txhawb nqa zaub mov, Folic Acid (Vitamin B9 / Pteroylglutamic Acid) yog ib qho tsis muaj - cov khoom noj tseem ceeb sib tham. Txawm li cas los xij, kev ruaj ntseg, siab -purity API uas tiv thaiv kev degradation thaum lub sij hawm ntev txee- lub neej yog qhov nyuaj rau cov tsim qauv.Xi'an Tihealthmuab cov neeg tseem ceeb-tier, synthetically derived Folic Acid Powder engineered rau siab tshaj plaws stability.
Ua raws li cov txheej txheem GMP nruj dhau los ntawm kev ua tiav ntau- cov txheej txheem ua kua thiab crystallization, peb cov Folic Acid tau lees paub qhov kev ntsuam xyuas purity ntawm 97.0% mus rau 102.0%, ua raws li USP, EP, thiab BP pharmacopoeia cov qauv. Kev nthuav qhia ua daj rau txiv kab ntxwv- daj microcrystalline hmoov, nws muaj cov qauv tsim tshwj xeeb rau cov vitamin prenatal multivitamins, B- cov tshuaj ntsiav tsis yooj yim, thiab loj- nplai hmoov / cereal fortification, xa cov bioavailable methyl- tus neeg mob precursors xav tau rau cellular DNA synthesis
1. Formulation Edge: Navigating Vitamin B9 ua
Rau cov kws tshawb fawb R&D, Folic Acid nthuav qhia txog kev txwv lub cev, tshwj xeeb yog hais txog solubility, lub teeb rhiab heev, thiab micro-dosing homogeneity. Peb cov khoom siv tshuaj nquag (API) tau ua kom zoo rau cov chaw lag luam no:
- Micro-Dosing Homogeneity:
- Folic acid yog dosed hauv micrograms (piv txwv li, 400mcg - 800mcg ib pab). Peb qhov kev tswj xyuas qhov loj me me ua kom muaj kev sib txuas ntawm geometric dilution thaum lub sij hawm qhuav sib tov, tiv thaiv "cov nqaij kub" (dhau -dosing) hauv koj cov ntsiav tshuaj zaum kawg lossis cov tshuaj ntsiav matrices.
- Solubility Engineering:
- Folic acid yog xyaum insoluble hauv dej txias thiab rhiab rau acidic pH. Txawm li cas los xij, nws dissolves yooj yim hauv dilute alkaline daws. Peb muab cov kev qhia meej meej rau cov kws tsim qauv tab tom nrhiav los tsim cov kua dej ruaj khov lossis cov tshuaj txhaj los ntawm kev siv cov tshuaj sodium-kev hloov pauv ntsev.
- Exceptional Photostability:
- Vitamin B9 degrades sai heev thaum raug UV teeb. Peb cov txheej txheem crystallization thiab downstream purification ua tau ib qho kev ruaj khov ntawm cov lattice qauv, uas, thaum ua ke nrog peb lub teeb - thaiv cov ntim ntau, ua kom xoom degradation thaum lub sij hawm kev thauj mus los thoob ntiaj teb thiab khaws cia.
2. Certificate of Analysis (USP/EP Qib TDS)
Batch-rau-batch sib xws thiab kev tswj nruj ntawm cov kuab tshuaj residual yog qhov tseem ceeb rau kev ua raws li kws tshuaj. Hauv qab no yog daim ntawv txheeb xyuas cov ntaub ntawv rau peb tus qauv Folic Acid API.
| Cov khoom kuaj | Specification txwv (USP) | Test Method / Standard |
|---|---|---|
| Physicochemical Properties | ||
| Qhov tshwm sim | Yellow rau txiv kab ntxwv- daj microcrystalline hmoov | Kev tshuaj xyuas qhov muag |
| Kev txheeb xyuas (IR) | Matches Reference Spectrum | Infrared Absorption<197K> |
| Assay (Purity ntawm Anhydrous Basis) | 97.0% – 102.0% | HPLC |
| Cov ntsiab lus dej | Tsawg dua lossis sib npaug li 8.5% | Karl Fischer Titration |
| Residue ntawm Ignition | Tsawg dua lossis sib npaug li 0.3% | 550℃Muffle Rauv |
| Impurities & Residual Solvents | ||
| Cov khoom sib txuas (Impurity A, thiab lwm yam) | Ua raws li USP monographs nruj me ntsis | HPLC |
| Residual Solvents | Ntsib USP<467>kev xav tau | GC-HS |
| Kev nyab xeeb & Cov kab mob | ||
| Heavy Metals (Pb, As, Cd) | Ua raws li cov kev txwv thoob ntiaj teb | ICP-MS |
| Tag Nrho Plate Count (TPC) | Tsawg dua lossis sib npaug li 1,000 CFU / g | FDA-BAM |
3. Thawj Lub Cev Muaj Zog (R&D Kev Pom Zoo)
Hloov cov ntaub ntawv kho mob uas tsis yog-raws li kev thov kev kho mob nrog cov txheej txheem tshawb fawb txog kev ua haujlwm, cov vitamin tseem ceeb no txhawb nqa cov qauv tsim nyog:
Kev noj zaub mov zoo nrog folate txaus tuaj yeem txo tus poj niam txoj kev pheej hmoo ntawm kev muaj menyuam hauv lub hlwb lossis tus txha caj qaum thaum yug los. Nws yog lub hauv paus tseem ceeb muaj nyob rau hauv prenatal multivitamin, tsav tsheb ceev cellular division thiab DNA synthesis thaum ntxov embryogenesis.
Folic acid ua synergistically nrog Vitamin B12 hauv kev tsim cov qe ntshav liab noj qab nyob zoo hauv cov pob txha pob txha. Nws yog ib qho tseem ceeb hauv kev tsim cov tshuaj ntxiv rau cov hom phiaj tseem ceeb, lub zog metabolism, thiab kev tiv thaiv kev noj haus macrocytic anemia.
Raws li ib qho tseem ceeb methyl- pub dawb, folic acid pab txhawb kev hloov pauv ntawm homocysteine rau hauv methionine. Kev tswj hwm qhov qub, noj qab nyob zoo ntawm cov ntshav homocysteine ntau pom zoo los ntawm cov kws kho mob noj zaub mov zoo yog qhov tseem ceeb biomarker rau ntev - lub sij hawm mob plawv thiab endothelial.
4. Cov phiaj xwm kev thov B2B
- Khoom noj khoom haus (Capsules & Tablets):
- API qhov tseem ceeb rau cov vitamins ua ntej yug menyuam, kev qhia B- cov qauv tsim, thiab kev paub txog kev txhawb nqa ntxiv. Feem ntau sib xyaw nrog maltodextrin rau precision micro-dosing.
- Yuav Tsum Muaj Khoom Noj Fortification:
- Kev xa tawm thoob plaws ntiaj teb hauv kev lag luam hmoov nplej, nplej polishing, thiab kev lag luam bakery ua haujlwm kom tau raws li tsoomfwv -tsim folate fortification qauv.
- Me nyuam mos & Maternity Nutrition:
- Cov qauv tsim nruj me ntsis rau hauv cov mis mos thiab cov khoom noj khoom haus rau niam txiv kom ntseeg tau tias kev loj hlob tseem ceeb tau ua tiav zoo.
- Kev Ua Si & Zog Khoom Noj:
- Ntxiv rau cov dej qab zib thiab cov hmoov rov qab los txhawb cov amino acid metabolism thiab ATP synthesis.
5. Advanced Chemical Synthesis Protocol
Peb cov Folic Acid yog tsim los ntawm cov kws kho mob cov lus qhia nruj, kom ntseeg tau siab tshaj plaws purity thiab ua tiav kev tshem tawm cov khoom phom sij:
- Condensation Reaction:
- Cov txheej txheem pib nrog kev tswj hwm tri-cov khoom sib xyaw ua ke ntawm 2,4,5-triamino-6-hydroxypyrimidine, p-aminobenzoyl-L-glutamic acid, thiab qhov tsim nyog peb-carbon reactant (xws li trichloroacetone) nyob rau hauv ib puag ncig .
- Kev kho pH & Crude Precipitation:
- Cov tshuaj tiv thaiv matrix yog ua tib zoo kho rau acidic pH (kwv yees . 2.5 - 3.0) kom precipitate crude folic acid compound, cais nws los ntawm cov tshuaj tiv thaiv niam cawv.
- Alkaline Refining & Decolorization:
- Cov matrix crude yog yaj nyob rau hauv ib tug me me sodium hydroxide (alkaline) tov. Cov pa roj carbon activated yog qhia kom nqus cov impurities thiab kho cov xim profile.
- Acid Re-Ntsuas & Ntxuav:
- Hydrochloric los yog sulfuric acid yog reintroduced rau precipitate lub siab purified Folic Acid. Tom qab ntawd nws rov qab ntxuav nrog dej deionized kom tshem tawm cov ntsev seem thiab cov kuab tshuaj.
- Lub tshuab nqus tsev ziab & Micronization:
- Lub ncuav mog qab zib ntub dej huv yog qhuav rau hauv cov kua dej tshwj xeeb- lub txaj tshuab ziab khaub ncaws ( khaws cia hauv qab 120℃los tiv thaiv thermal degradation) thiab micronized kom ua tiav USP kawg - qib microcrystalline hmoov.
6. Kev Ruaj Ntseg Ntim & Kev Lag Luam Thoob Ntiaj Teb
Folic acid yog rhiab heev rau UV teeb. Ua haujlwm hauv qab ibISO9001: 2015 & GMP Kev Tswj Xyuas Zoo, Xi'an Tihealth siv lub teeb - thaiv, siab - ntim ntim kom ntseeg tau tias xoom degradation thaum caij tsheb npav.
| Qauv hnyav | Ntim Hom | Kev Lag Luam Loj | Ntim Hom |
| 1kg - 5kg | Opaque, Nqus -Aluminium Foil Hnab kaw | 25kg ua | Hnyav-Lub luag haujlwm Cardboard Nruas nrog Ob Chav Opaque PE Liners |
Tiv tauj peb rau Lag luam wholesale Quotes & Lab Reports
7. Formulation & Technical FAQ
Yuav ua li cas yaj Folic Acid rau cov kua formulations?
Ntshiab folic acid yog xyaum insoluble nyob rau hauv nruab nrab dej thiab ethanol. Txhawm rau tsim cov kua dej los yog dej haus, cov pab pawg R & D yuav tsum siv cov tshuaj dilute alkaline (xws li sodium hydroxide lossis sodium carbonate) los hloov cov hmoov mus rau hauv cov ntsev sodium folate. Peb pom zoo kom nruj tswj pH kawg kom tsis txhob rov- nag lossis daus.
Koj puas muab triturated (diluted) folic acid blends rau kev tsim khoom yooj yim dua?
Yog lawm. Vim tias qhov yuav tsum tau noj txhua hnub ntawm folic acid yog qhov tsawg heev (400 mcg), ua tiav kev sib xyaw ua ke nrog 99% ntshiab API tuaj yeem nyuaj rau qee qhov chaw. Raws li qhov kev thov, peb tuaj yeem muab qhov tseeb -triturated blends (piv txwv li, 1% lossis 10% folic acid) ntawm cov neeg nqa khoom xws li maltodextrin lossis dicalcium phosphate los ua kom koj cov khoom lag luam.
Qhov no puas yog synthetically derived los yog muab rho tawm los ntawm cov zaub mov?
Peb cov Folic Acid (Pteroylglutamic Acid) yog muab los ntawm synthetically derived. Hauv kev lag luam tshuaj thiab kev tiv thaiv kev lag luam, hluavtaws folic acid yog universally nyiam tshaj cov zaub mov- tau txais folates vim tias nws ruaj khov dua nyob rau hauv tshav kub / lub teeb thiab muaj ntau dua bioavailability tus nqi rau tib neeg nqus.
Cim npe nrov: Tuam Tshoj folic acid hmoov manufacturers, lwm tus neeg, Hoobkas
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